Bionovo To Advance Menerba To Phase 3 Clinical Testing In EuropeBionovo, Inc. (Nasdaq: BNVI) announced that it has received final guidance from the European Medicines Agency (EMA) in order to advance Menerba, the company's lead drug candidate for menopausal symptoms, to Phase 3 clinical trials in Europe. The guidance defines the clinical and regulatory pathway to a European marketing authorization for Menerba...
Hormonal Birth Control Alters Scent Communication In Primates Hormonal contraceptives change the ways captive ring-tailed lemurs relate to one another both socially and sexually, according to a Duke University study that combined analyses of hormones, genes, scent chemicals and behavior. Contraception alters the chemical cues these scent-reliant animals use to determine genetic fitness, relatedness and individuality...
Bone Plays Key Role In Insulin Regulation New US research on mice suggests that bone plays a key role in insulin regulation and helps cells of the body take up glucose; as both these processes are impaired in people with type 2 diabetes the researchers suggest this discovery could lead to new diabetes drugs...
Study Suggests Link Between Metabolic Disease, Bone Mass In MiceA new study by Johns Hopkins researchers has found that insulin, the sugar-regulating hormone, is required for normal bone development and that it may provide a link between bone health and metabolic disease, such as diabetes. The study, headed by Thomas Clemens, Ph.D...
Subtle Thyroid Problem Triples The Risk Of Placental Separation In BirthPregnant women with antibodies that can indicate early thyroid disease are three times as likely to have placental separation during labor, researchers at UT Southwestern Medical Center have found in a study of more than 17,000 women. The findings, however, do not indicate that there would be any benefit from routinely screening pregnant women for thyroid problems, the researchers said...
Protein Crucial In Diabetes May Be Central Player In Other Diseases TooStudying a protein already known to play an important role in type 2 diabetes and cancer, genomics researchers have discovered that it may have an even broader role in disease, particularly in other metabolic disorders and heart disease. In finding unsuspected links to other disease-related genes, the scientists may have identified future targets for drug treatments...
Researchers Block Pathway That Performs Key Function In End-Stage Prostate CancerProstate cancer advances when tumors become resistant to hormone therapy, which is the standard treatment for patients, and begin producing their own androgens. Researchers at UT Southwestern Medical Center have found that blocking one of the enzymatic steps that allow the tumor to produce androgens could be the key in halting a tumor's growth...