New Clues On How ApoE4 Affects Alzheimer's RiskCommon variants of the ApoE gene are strongly associated with the risk of developing late-onset Alzheimer's disease, but the gene's role in the disease has been unclear. Now, researchers funded by the National Institutes of Health have found that in mice, having the most risky variant of ApoE damages the blood vessels that feed the brain...
Controlling Inflammation: Novel Drug Candidates Offer New RoutePursuing a relatively untapped route for regulating the immune system, an international team of researchers has designed and conducted initial tests on molecules that have the potential to treat diseases involving inflammation, such as asthma, rheumatoid arthritis, stroke and sepsis...
Minimizing Stroke DamageFollowing a stroke, factors as varied as blood sugar, body temperature and position in bed can affect patient outcomes, Loyola University Medical Center researchers report. In a review article in the journal MedLink Neurology, first author Murray Flaster, MD, PhD and colleagues summarize the latest research on caring for ischemic stroke patients...
High Volume Stroke Centers Provide Faster Treatment And Have Superior Outcomes According to a study published online in the Journal of NeuroInterventional Surgery, patients who attend stroke centers with a high volume of patients are treated faster and have better outcomes. Findings from the study are based on 442 patients with the average age of 66, treated with endovascular therapy at 9 specialist (tertiary) stroke centers between September 2009 and July 2011...
Speed Drawing Ability May Predict Subsequent Stroke Death Risk Stroke remains one of the leading causes of mortality and disability, even though there have been advances in treatment. Older men who have impaired cognitive function prior to a stroke are at increased risk of subsequent disability and mortality...
Blood Clot Prevention In A Dietary SupplementA compound called rutin, commonly found in fruits and vegetables and sold over the counter as a dietary supplement, has been shown to inhibit the formation of blood clots in an animal model of thrombosis...
Stroke Prevention Procedure For Patients With A-Fib Who Can't Take Blood ThinnersPatients with atrial fibrillation (A-fib) who cannot take blood thinners now have an alternative to reduce their risk of stroke, which is five times more common in people with the rhythm disorder. The non-surgical procedure works by tying off the left atrial appendage (LAA), the source of most blood clots leading to stroke in patients with A-fib...
Updated Treatment Guidelines For Aneurysmal Subarachnoid HemorrhagePatients who are diagnosed in the emergency room with a specific type of brain bleed should be considered for immediate transfer to a hospital that treats at least 35 cases a year, according to a new scientific statement from the American Heart Association/American Stroke Association...
JAM-A Protein Keeps Blood Clots In CheckCut your toe, and platelets -- those disc-shaped cells circulating in your blood -- rush to the scene, clumping together to plug the leak. But when an unwanted clot forms in an artery, and an overaccumulation of platelets blocks blood flow, a heart attack or stroke occurs, too often with fatal results...
Thrombus Aspiration And Stents In PCI - Long-term Outcome SimilarNew research confirms thrombus aspiration (TA) during percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI) provides long-term outcomes similar to conventional intervention with bare-metal or drug-eluting stents...
Cardiovascular Risk From NSAIDsAfter nearly 13 years of study and intense debate, a pair of new papers from the Perelman School of Medicine, at the University of Pennsylvania have confirmed exactly how a once-popular class of anti-inflammatory drugs leads to cardiovascular risk for people taking it...
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