Compounds To Block Immune-Regulating EnzymeScientists at The Scripps Research Institute have found the first chemical compounds that act to block an enzyme that has been linked to inflammatory conditions such as asthma and arthritis, as well as some inflammation-promoted cancers...
'Barcoding' Viruses For Rapid Detection Of Mutated StrainsDr Julian Hiscox and Dr John Barr of the University's Faculty of Biological Sciences are working with the Health Protection Agency Porton (HPA) to build a bank of molecular signatures that will help identify the severity of virus infection from characteristic changes seen in cells...
Education, Medication Compliance Cited In Lower Number Of ICU Admissions For AsthmaA review of 30 years of life-threatening asthma cases in a San Antonio intensive care unit found that annual ICU admissions for the condition have dropped 74 percent. The study, by UT Medicine San Antonio physicians who reviewed cases at University Hospital between 1980 and 2010, also showed intubation in the emergency department to help patients breathe did not result in longer hospital stays...
Gene Discovered That Causes Joubert SyndromeC5ORF42 was identified as the gene that causes Joubert Syndrome in a number of families in the Lower St. Lawrence region of Quebec where the causal gene had remained unknown since the initial description of the syndrome in 1969. This is what a study in The American Journal of Human Genetics reveals...
Distinguishing Between Tuberculosis And Sarcoidosis Using BiosignaturesWith a range of diseases, doctors need unique features which they can use to unequivocally identify a patient's illness for an appropriate diagnosis. Scientists therefore search for the biomarkers for an illness or a combination of biomarkers, known as biosignatures, which are as easy as possible to measure...
Loss Of Biodiversity May Lead To Increase In Allergies And AsthmaDeclining biodiversity may be contributing to the rise of asthma, allergies, and other chronic inflammatory diseases among people living in cities worldwide, a Finnish study suggests. Emerging evidence indicates that commensal microbes inhabiting the skin, airway, and gut protect against inflammatory disorders. However, little is known about the environmental determinants of the microbiome...
More Cases But Fewer Deaths Relating To Pneumococcal DiseaseThe vaccine given to children to immunise against serious pneumococcal disease does not offer full protection, reveals research from the Sahlgrenska Academy at the University of Gothenburg, Sweden, finding that the number of cases diagnosed has tripled over the past 50 years. Each year an estimated 1 million children worldwide die as a result of pneumococcal disease...
Many Asthmatic Athletes May Not Be Using Best Therapy Asthma is an extremely common condition amongst elite athletes; one of whom is marathon runner Paula Radcliffe. Since the 70s, the numbers of athletes suffering from asthma has gradually risen at almost every Olympics, and in 2004, nearly 21% of Team GB had asthma, in comparison to 8% of the British population...
Silicosis Is Still A Major Killer Globally Free crystalline silicon dioxide, or silica, is one of the most common minerals worldwide. It is used to manufacture many items, including glass, bottles, ceramics, but it is also a common additive in the production of foods where it is primarily used as a flow agent in powdered foods or to absorb water...