Medical Animation Lupus

Guidelines For Management Of Lupus Nephritis Issued By The American College Of Rheumatology
The American College of Rheumatology (ACR) has issued newly created guidelines for the screening, treatment, and management of lupus nephritis - a severe manifestation of systemic lupus erythematosus (SLE) where the disease attacks the kidneys. Previously, only general guidelines for SLE existed for clinicians...

Lupus Nephritis - New Guidelines Issued
Lupus nephritis is a kidney disorder caused by a complication of systemic lupus erythematosus (SLE). Unlike previous guidelines, the new ACR guidelines are specific to lupus nephritis and include newer treatments, techniques for detecting renal disease, as well as treatment of pregnant SLE patients with kidney involvement. The guidelines are published in Arthritis Care & Research...

A Link Between Atherosclerosis And Autoimmunity
Individuals who suffer from autoimmune diseases also display a tendency to develop atherosclerosis - the condition popularly known as hardening of the arteries. Clinical researchers at LMU, in collaboration with colleagues in Würzburg, have now discovered a mechanism which helps to explain the connection between the two types of disorder...

Epstein Barr Virus Protects Against Autoimmunity
To the surprise of investigating researchers, an animal model of Epstein Barr virus protected lupus-prone mice against development of the autoimmune disease. Earlier work had suggested that EBV might promote the development of autoimmunity. "We were completely surprised. So, we redid the experiments, and the results came out the same," said Dr...

3 New Lupus Genes Discovered Through International Collaboration
Three newly confirmed lupus genes are opening new avenues of research at the Oklahoma Medical Research Foundation. A paper published in the April 6 issue of the American Journal of Human Genetics describes three lupus genes discovered by OMRF researchers as part of a massive international collaboration...

R-Loops Break Walls Of Gene Silencing
Researchers at the University of California, Davis, have figured out how the human body keeps essential genes switched "on" and silences the vast stretches of genetic repeats and "junk" DNA. Frédéric Chédin, associate professor in the Department of Molecular and Cellular Biology, describes the research in a paper published in the journal Molecular Cell...

New Targets For Lupus Treatment Inspired By Natural Method For Clearing Cellular Debris
Cells that die naturally generate a lot of internal debris that can trigger the immune system to attack the body, leading to diseases such as lupus. Now Georgia Health Sciences University researchers report that an enzyme known to help keep a woman's immune system from attacking a fetus also helps block development of these autoimmune diseases that target healthy tissues, such as DNA or joints...

Arthritis and Lupus Linked To Lower Birth Rates
A multi-center study of a national survey published in Arthritis Care and Research, a journal of the American College of Rheumatology (ACR), has established that over half of women with rheumatoid arthritis (RA) and systematic lupus erythematosus (SLE) have fewer children than desired. Leading researcher, Kaleb Michaud, Ph.D...

Women With Rheumatoid Arthritis And Lupus Give Birth To Fewer Children
New research shows that more than half of women with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) have fewer children than desired...

Mutation Drives Viral Sensors To Initiate Autoimmune Disease
A new study uses a mouse model of a human autoimmune disease to reveal how abnormal regulation of the intracellular sensors that detect invading viruses can lead to autoimmune pathology...

DNA Sequence Discovered That Causes The Most Severe Cases Of Lupus
A "genetic accelerator" is responsible for the most severe cases of Lupus (systemic lupus erythemathosus), an autoimmune disease: the accelerator, called enhancer HS1.2, speeds up the activity of some critical genes of the immune system involved in the disease. A team of Italian researchers at the Catholic University of Sacred Heart in Rome found that the enhancer HS1...

32 Million Americans Have Autoantibodies That Target Their Own Tissues
More than 32 million people in the United States have autoantibodies, which are proteins made by the immune system that target the body's tissues and define a condition known as autoimmunity, a study shows...

Study: Mycophenolate Is Superior To Azathioprine As Treatment For Lupus Nephritis
A new large, international study finds that the immunosuppressant drug mycophenolate mofetil is superior to azathioprine, an older immunosuppressant, as a maintenance therapy for lupus nephritis...

Hemodialysis Therapy Preferred By Most Lupus Nephritis Patients With End-Stage Renal Disease
Newly published research shows that more patients with end-stage renal disease (ESRD) caused by lupus nephritis choose hemodialysis as their initial kidney replacement therapy over peritoneal dialysis and preemptive kidney transplantation...

Transportation And Childcare Difficulties Top Reasons For Missed Lupus Appointments
The first step towards successful medical care is to see a physician, but for some patients this isn't as simple or easy as it may sound. A study presented at the 2011 Annual Scientific Meeting of the American College of Rheumatology in Chicago, finds that many lupus patients with low socioeconomic status are unable to attend scheduled appointments with physicians due to daily obstacles...