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Unexpected Source Of Diabetic Neuropathy Pain Discovered
Nearly half of all diabetics suffer from neuropathic pain, an intractable, agonizing and still mysterious companion of the disease. Now Yale researchers have identified an unexpected source of the pain and a potential target to alleviate it...
Idiopathic Toe Walking And Rotator Cuff Surgery Highlighted In May JAAOS
Treatments for Idiopathic Toe Walking Based on Child's Age and Severity of Gait Abnormality Most children develop a normal walking pattern, or gait, by age 2. And while some toe walking - where a child primarily walks on the front of the foot or toes, never touching the heel to the ground - is common, persistent toe walking beyond age 2 may indicate a neurological disorder...
Marijuana Helps Relieve MS Pain
Researchers from the University of California, San Diego School of Medicine have found that smoking marijuana can help relieve pain, and muscle tightness "spasticity" in individuals with multiple sclerosis (MS). The study is published in the Canadian Medical Association Journal (CMAJ)...
During An Injection, Look Away If You Want To Avoid Pain
Health professionals commonly say, "Don't look and it won't hurt" before administering an injection, but is there any scientific basis for the advice? A group of German investigators has found that, in fact, your past experience with needle pricks, along with information you receive before an injection, shape your pain experience. Their research is published in the May issue of Pain®...
Different Mechanisms Of Pain Discovered Which Suggest New Strategies For Drug Development
Researchers at the University of Leeds have found a previously unknown mechanism through which pain is signalled by nerve cells - a discovery that could explain the current failings in the drug development process for painkillers and which may offer opportunities for a new approach...
Some Symptoms Of Multiple Sclerosis Respond To Smoked Cannabis
A clinical study of 30 adult patients with multiple sclerosis (MS) at the University of California, San Diego School of Medicine has shown that smoked cannabis may be an effective treatment for spasticity - a common and disabling symptom of this neurological disease...
New Study Discovers Powerful Function Of Single Protein That Controls Neurotransmission
Scientists at Weill Cornell Medical College have discovered that the single protein - alpha 2 delta - exerts a spigot-like function, controlling the volume of neurotransmitters and other chemicals that flow between the synapses of brain neurons...
Unsedated Transnasal Endoscopy To Screen For Esophageal Disease Is Safe And Feasible
Researchers report that unsedated transnasal endoscopy is a feasible, safe, and well-tolerated method to screen for esophageal disease in a primary care population. This study is the largest reported experience with transnasal endoscopy in the United States...
New Lyrica Oral Formulation For Patients With Dysphagia Available In UK
Lyrica® (pregabalin) is now available in a new strawberry-flavored oral solution form in the UK, in order to benefit patients who have difficulty in taking medication in capsule form or for those with dysphagia (swallowing difficulty)...
What Is Diabetic Neuropathy?
Diabetic neuropathy is damage that affects the peripheral nerves of the body. The damage is specifically to the nerves of the ganglia, outside of the skull, the spinal cord, and some other nerves that aid the body in assisting fundamental organs, such as the heart, bladder, intestines, and stomach. Diabetic neuropathy refers only to individuals who have diabetes...
Reduction In Deaths After The Painkiller Co-Proxamol Withdrawn In The UK
During the six years following the withdrawal of the analgesic co-proxamol in the UK in 2005, there was a major reduction in poisoning deaths involving this drug, without apparent significant increase in deaths involving other analgesics. These are the findings of a study by Keith Hawton of the University of Oxford, UK and colleagues and published in this week's PLoS Medicine...
Extramedical Pain Reliever Usage More Likely During Mid-Asolescence
According to a study published Online First by Archives of Pediatrics & Adolescent Medicine, teenagers in the United States are more likely to use prescription pain relievers to get high or for other unapproved indications (extramedical use) during mid-adolescence...
16 Years Olds At Greatest Risk For Misusing Prescription Drugs
The peak risk for misusing prescription pain relievers occurs in mid-adolescence, specifically about 16 years old and earlier than many experts thought, according to a new study by Michigan State University researchers. The results, based on recent nationwide surveys of nearly 120,000 U.S...
Waking Embryos Before They Are Born
Under some conditions, the brains of embryonic chicks appear to be awake well before those chicks are ready to hatch out of their eggs. That's according to an imaging study published online in Current Biology, a Cell Press publication, in which researchers woke chick embryos inside their eggs by playing loud, meaningful sounds to them...
Lyrica (pregabalin) No Good For Diabetes Or HIV Associated Neuropathic Pain
Lyrica (pregabalin) failed in two separate human trials to reduce neuropathic pain linked to diabetes or HIV, said makers Pfizer today. One of the trials - Phase III HIV neuropathy - was stopped early because no benefits were found in an interim analysis on 246 patients out of a planned 416...
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