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Hospitals In Large Cities May Act As Breeding Grounds For The Superbug MRSA Prior To It Spreading To Smaller Hospitals
Hospitals in large cities act as breeding grounds for the superbug MRSA prior to it spreading to smaller hospitals, a study suggests. Researchers found evidence that shows for the first time how the superbug spreads between different hospitals throughout the country...

Link Between Healthcare-Associated Infections And Expensive Hospital Readmissions
New research finds a strong link between healthcare-associated infections (HAIs) and patient readmission after an initial hospital stay...

Drug-resistant Bacteria - Designing Nanoparticles For High Antibiotic Doses
Highly-targeted nanoparticles that deliver huge doses of existing antibiotics could be used to overload the defenses of drug-resistant bacteria, researchers from Brigham and Women's Hospital and MIT reported in the journal ACS Nano...

Five Fold Increase In Antimicrobial Resistance For Common UTI Drug Seen Since 2000
In a surveillance study of over 12 million bacteria, investigators at The George Washington University and Providence Hospital found E. coli antimicrobial resistance to ciprofloxacin, the most commonly prescribed antimicrobial for urinary tract infections in the U.S., increased over five-fold from 2000 to 2010...

African Malaria Parasite Is Genetically Resistant To Best Anti-Malarial Drugs
An online report in Malaria Journal reveals that scientists have discovered genetic mutations in the deadliest malaria parasite in Africa that makes them resistant to one of the most powerful anti-malarial drugs. The researchers point out that the finding is a stark reminder that even the best weapons against malaria could become obsolete...

Researchers Have A Natural Sidekick That May Resolve The Antibiotic-Resistant Bacteria Dilemma
Antibiotic-resistant bacteria continue to be a global concern with devastating repercussions, such as increased healthcare costs, potential spread of infections across continents, and prolonged illness. However, researchers at Brigham and Women's Hospital (BWH) could change the playing field of man versus bacteria...

Quickly Spreading Gene Linked To Asian MRSA Epidemic
National Institutes of Health (NIH) scientists and their colleagues in China have described a rapidly emerging Staphylococcus aureus gene, called sasX, which plays a pivotal role in establishing methicillin-resistant S. aureus (MRSA) epidemics in most of Asia. Senior author Michael Otto, Ph.D...

Transmission Of MRSA Between Mothers And Newborns Examined
The need to swab the noses of pregnant women and newborns for the presence of MRSA (methicillin-resistant Staphylococcus aureus) may be unfounded, according to a Vanderbilt study now available online and published in the May issue of Pediatrics. The study's senior author, Buddy Creech, M.D...

Valid Therapeutic Target Identified In Acute Myeloid Leukemia
Through a groundbreaking new gene sequencing technology, researchers have demonstrated that the gene FLT3 is a valid therapeutic target in Acute Myeloid Leukemia, AML, one of the most common types of leukemia. The technique, developed by Pacific Biosciences, allows for the rapid and comprehensive detection of gene mutations in patients with AML...

Anti-Superbug Clues In Deep, Isolated Cave
A deep, isolated cave in New Mexico harbors strains of antibiotic-resistant bacteria that might hold clues for fighting modern-day superbugs. The hope is the discovery means there are previously unknown antibiotics occurring naturally, that could be used to treat infections...

For Drug-Resistant Cancers, Kinase Test May Yield Big Gains
In a paper published in the journal Cell, a team from the University of North Carolina at Chapel Hill unveils the first broad-based test for activation of protein kinases "en masse", enabling measurement of the mechanism behind drug-resistant cancer and rational prediction of successful combination therapies...

Antibiotic-Resistant Bacteria Found Deep In Unspoiled Underground Caves May Be Key To New Antibiotics
McMaster University and University of Akron researchers are leading the way in understanding the origins of antibiotic resistance, a global challenge that is creating a serious threat to the treatment of infectious diseases. Gerry Wright, scientific director of the Michael G...

Preventing Infection In Cardiac Devices
Bacteria such as Staphylococcus aureus, the 'superbug' behind MRSA, can be a major problem for patients who have a medical implant, such as a replacement heart valve or pacemaker. Bacteria are able to form colonies - called biofilms - on the implanted device, which can lead to wider infections such as endocarditis, a bacterial infection of the heart...

FDA Issues Guidance For Antibiotic Use In Farm Animals
The FDA announced today that it wants to take action to protect public health in regards to the use of antibiotics in food producing animals. The issue has been in the media recently with reports of farmers treating livestock with barrages of antimicrobial drugs for no compelling reason...

Novel Method To Combat Malaria Drug Resistance
Researchers from the University of Notre Dame's Eck Institute for Global Health developed a "gene chip" to contribute to the identification of malaria drug resistance, an effort that will allow for real-time response in modified treatment strategies for this devastating disease. The new discovery is described in a paper appearing in the latest early online edition of the journal Science...