DNA Sequence Discovered That Causes The Most Severe Cases Of LupusA "genetic accelerator" is responsible for the most severe cases of Lupus (systemic lupus erythemathosus), an autoimmune disease: the accelerator, called enhancer HS1.2, speeds up the activity of some critical genes of the immune system involved in the disease. A team of Italian researchers at the Catholic University of Sacred Heart in Rome found that the enhancer HS1...
Transportation And Childcare Difficulties Top Reasons For Missed Lupus AppointmentsThe first step towards successful medical care is to see a physician, but for some patients this isn't as simple or easy as it may sound. A study presented at the 2011 Annual Scientific Meeting of the American College of Rheumatology in Chicago, finds that many lupus patients with low socioeconomic status are unable to attend scheduled appointments with physicians due to daily obstacles...
Successful Pregnancy Outcomes For Most Women With LupusPromising research led by investigators at Hospital for Special Surgery may offer hope for women with lupus who once thought that pregnancy was too risky. Results from the multicenter National Institutes of Health (NIH) funded PROMISSE initiative, being presented Monday, Nov. 7 and then during a press conference on Tuesday, Nov...
XToll Completely Prevented Cutaneous Lupus In Animal Study CBio Limited have announced the publication of their animal trial on the advanced access site of the Oxford Journals publication, Nephrology Dialysis Transplantation. The research is titled - "Recombinant chaperonin10 (Xtoll) suppresses cutaneous lupus and lupus nephritis in MRL-(Fas)lpr mice." According to results of the study, using XToll to treat mice completely prevented cutaneous lupus...
Statins Disappoint In Atherosclerosis Progression In Children With LupusAccording to the American College of Rheumatology (ACR) 322,000 adult Americans are affected by systemic lupus erythematosus (SLE) with approximately 5,000 to 10,000 children in the U.S. affected by lupus (Lehman 1996), although exact figures for pediatric SLE cases remain difficult to establish...
Continued Treatment For Lupus May Boost Survival Of Those Patients With End-Stage Kidney DiseaseResearchers at Albert Einstein College of Medicine of Yeshiva University have shown that close supervision by rheumatologists and the use of immunosuppressant drugs improve the survival of lupus patients with end-stage kidney disease a finding that could reverse long-standing clinical practice. Their study appeared in the September 1 online edition of the Journal of Rheumatology. At least 1...
New Genetic Clue In The Development Of Rheumatoid ArthritisScientists at Mount Sinai Hospital, in collaboration with researchers at the University of Toronto, University Health Network and McGill University have obtained significant new insights into the causes of rheumatoid arthritis (RA) and other autoimmune disorders including type 1 diabetes, lupus and Graves disease...
Gender Difference In Autoimmune Disease Explained By Newly Discovered B CellsResearchers at National Jewish Health have discovered a type of cell that may contribute to autoimmune disease. The findings also suggest why diseases such as lupus, multiple sclerosis and rheumatoid arthritis strike women more frequently than men. The cells, a subset of immune-system B cells, make autoantibodies, which bind to and attack the body's own tissue...