Gout Animations

Teens With Abnormal Levels Of Uric Acid At Increased Risk For Hypertension
Teens with high levels of uric acid appear to be at increased risk for high blood pressure, according to results of research from scientists at Johns Hopkins Children's Center...

Hot On The Trail Of Metabolic Diseases And Antibiotic Resistance
ABC transporters are membrane proteins that actively pump a wealth of molecules across the membrane. Over 40 different ABC transporters perform vital functions in humans. Genetic defects in ABC transporters can trigger metabolic diseases such as gout, neonatal diabetes or cystic fibrosis, and certain ABC transporters also cause resistance to a wide range of drugs...

Clinical Trial Demonstrates That Rilonacept Significantly Reduces Gout Flares
A phase II clinical trial found that rilonacept, an inhibitor of the protein interleukin-1 (IL-1), significantly reduced acute gout flares that occur when initiating uric acid-lowering therapy...

Gout Flares - Rilonacept Effective, According To Clinical Trial
According to a phase II clinical trial, the drug rilonacept, which inhibits the protein interleukin-1 (IL-1), substantially reduces acute gout flares that occur at the start of uric acid-reducing therapy and is noted to be generally well tolerated with no serious infections or serious adverse events occurring in relation to the treatment...

Regeneron Announces FDA Acceptance Of ARCALYST® (rilonacept) Supplemental Biologics License Application For Review
Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) announced that the U.S. Food and Drug Administration (FDA) has accepted for review the Company's supplemental Biologics License Application (sBLA) for ARCALYST Injection for Subcutaneous Use for the prevention of gout flares in patients initiating uric acid-lowering therapy...

Preventing Gout Flare Ups In Patients With Renal Impairment - Dosing Guidance
Results from a new pharmacokinetic (PK) study presented at the annual meeting of the American College of Rheumatology (ACR) provide new evidence-based guidance for healthcare providers on using colchicine for gout flare prophylaxis in the presence of renal impairment...

Gout Cases Missed By Traditional Tests Often Detected By CT Scans
X-ray images known as CT scans can help confirm gout in patients who are suspected of having the painful condition but receive negative results from traditional tests, a Mayo Clinic study has found. The type of CT scan analyzed, dual-energy computed tomography, is also valuable for diagnosing people who cannot be tested with the typical method of drawing fluid from joints, researchers found...

American College Of Rheumatology 2011 Annual Meeting: Presentations By NYU Langone Experts
Experts from NYU Langone Medical Center will present new research findings and clinical insight into the treatment of rheumatic and bone diseases in a variety of presentations at the American College of Rheumatology (ACR) 2011 Annual Scientific Meeting in Chicago, November 5-9, 2011...

Unsuitable Footwear Linked To Foot Impairment And Disability In Gout Patients
New research shows that use of poor footwear is common among patients with gout. According to the study published in Arthritis Care & Research, a peer-reviewed journal of the American College of Rheumatology (ACR), gout patients who make poor footwear choices experienced higher foot-related pain, impairment and disability...

Pegloticase, Alternative Treatment For Chronic Gout Shows Greater Improvement In Symptoms
According to a study in the August 17 issue of JAMA, patients with severe, chronic gout who took pegloticase for 6 months as an alternative to conventional gout treatment that some patients may not respond to, showed greater improvements of uric acid levels as well as physical function and quality of life...

New Drug Aids Gout Patients Not Helped By Standard Treatments
Injections of pegloticase, a modified porcine enzyme, can produce significant and sustained clinical improvements in 2 out of 5 patients with chronic gout that is resistant to conventional therapies, researchers report in the August 17, 2011, issue of JAMA...

Pegloticase Helps Patients With Severe, Chronic Gout
Individuals with severe, chronic gout who have not responded to conventional treatment may benefit from six-months' worth of pegloticase treatment. Researchers from Duke University Medical Center, Durham, N.C., reported in JAMA (Journal of the American Medical Association) that individuals experienced better levels of uric acid as well as physical function, quality of life, and less pain...

Increase In Obesity And Hypertension Are Likely Contributors To The Increase In Gout Prevalence In US Over Last 2 Decades
A new study shows the prevalence of gout in the U.S. has risen over the last twenty years and now affects 8.3 million (4%) Americans. Prevalence of increased uric acid levels (hyperuricemia) also rose, affecting 43.3 million (21%) adults in the U.S...

Got The Gout? Self Reported Cases Show Increase In Prevalence
Eight million Americans, almost 6% of men and 2% of women have got the gout, a painful affliction in which uric acid crystals are deposited in the joints. In a self reported survey, the prevalence of gout continues to climb along with rates of related conditions such as hypertension and metabolic syndrome, reaching 3.9% in 2008, according to a new study released this week...

Lower Doses Of Anti-Gout Drug Recommended
Health professionals should ensure they are prescribing correct doses of colchicine, a treatment for acute gout, after three elderly patients were hospitalised within a fortnight, doctors at St Vincent's Hospital in Sydney say in a letter published in the Medical Journal of Australia...