Genes Linked To Alzheimer's Are The Same For Early- And Late-OnsetThe same gene mutations linked to inherited, early-onset Alzheimer's disease have been found in people with the more common late-onset form of the illness. The discovery by researchers at Washington University School of Medicine in St. Louis may lead doctors and researchers to change the way Alzheimer's disease is classified...
Genetic Connection To Traumatic ExperienceRutgers scientists have uncovered genetic clues as to why some mice no longer in danger are still fearful while others are resilient to traumatic experiences - knowledge that could help those suffering with crippling anxiety and PTSD...
Improving Understanding Of Human Diseases With 3D Mapping Of Human GenomeGenome Institute of Singapore's (GIS) Associate Director of Genomic Technologies, Dr Yijun RUAN, led a continuing study on the human genome spatial/structural configuration, revealing how genes interact/communicate and influence each other, even when they are located far away from each other...
Circular RNAs More Common Than Previously ThoughtIn the classical model of gene expression, the genetic script encoded in our genomes is expressed in each cell in the form of RNA molecules, each consisting of a linear string of chemical "bases"...
Chaos In The Cell's Command CenterA defective operating system is never a good thing. Like computers, our cells depend on operating systems to drive normal functions. Gene expression programs comprise the software code our cells rely on, with each cell type controlled by its own program. Corrupted programs can trigger disease...
Dyslexia-Linked Genetic Variant Decreases Midline Crossing Of Auditory PathwaysFinnish scientists have found that a rare dyslexia-linked genetic variant of the ROBO1 gene decreases normal crossing of auditory pathways in the human brain. The weaker the expression of the gene is, the more abnormal is the midline crossing. The results link, for the first time, a dyslexia-susceptibility gene to a specific sensory function of the human brain...
Osteoporosis Drug Complications Linked To Genetic FactorsAccording to a study published in the online version of the journal The Oncologist, a genetic variation that increases the risk of individuals who take bisphosphonates, developing serious necrotic jaw bone lesions, has been identified by researchers at the Columbia University College of Dental Medicine...
A New Genetic Subtype Of Lung Cancer DefinedA report from investigators at the Massachusetts General Hospital (MGH) Cancer Center has defined the role of a recently identified gene abnormality in a deadly form of lung cancer. Tumors driven by rearrangements in the ROS1 gene represent 1 to 2 percent of non-small-cell lung cancers (NSCLC), the leading cause of cancer death in the U.S...
How Genes Are Affected By Weightlessness - A Fly's PerspectiveOn Earth all biology is subjected to gravity. Some biological systems require gravity for correct orientation (geotropism: plants grow up, roots grow down). In the absence of gravity even human biology is affected: astronauts lose bone density at 1-2% a month rather than the usual 1-2% a year on Earth. But the effects of gravity on cellular processes are less well understood...