Keppra® Approved By FDA For Childhood Seizures In the U.S., Keppra® has been approved as adjunctive therapy for partial onset seizures in adults and children aged four years and older with epilepsy. However the UCB recently announced that the U.S. Food and Drug Administration (FDA) has now approved to lower the age restriction to include infants from the age of one month and older with epilepsy. Professor Dr...
A Step Closer To Unlocking A Mystery That Causes Epileptic Seizures In BabiesBenign familial infantile epilepsy (BFIE) has been recognised for some time as infantile seizures, without fever, that run in families but the cause has so far eluded researchers. However clinical researchers at the University of Melbourne and Florey Neurosciences Institute and molecular geneticists at the University of South Australia have discovered a gene...
Guidelines Stress Caution When Combining Anti-Epileptic, HIV Drugs New guidelines from the American Academy of Neurology will help physicians better choose seizure drugs for people on HIV/AIDS medication, avoiding deadly drug interactions and preventing critical anti-HIV drugs from becoming less effective, possibly leading to a more virulent strain of the disease...
Epilepsy And Violent Crime Not LinkedAccording to a large Swedish investigation published in PloS Medicine, epilepsy is not directly linked to an increased risk of committing violent crime. Although, individuals who previously experienced traumatic brain injury (TBI) have an increased risk of committing violent crime...
An Answer To A Mysterious Movement Disorder Discovered In The GenomeChildren with a rather mysterious movement disorder can have hundreds of attacks every day in which they inexplicably make sudden movements or sudden changes in the speed of their movements. New evidence reported in an early online publication from the January 2012 inaugural issue of Cell Reports, the first open-access journal of Cell Press, provides an answer for them...
Childhood Disorder Called PKD Linked To Genetic MutationsA large, international team of researchers led by scientists at the University of California, San Francisco has identified the gene that causes a rare childhood neurological disorder called PKD/IC, or "paroxysmal kinesigenic dyskinesia with infantile convulsions," a cause of epilepsy in babies and movement disorders in older children...
Superior Drug Combo For Difficult-To-Control EpilepsyA combination of two common drugs, lamotrigine and valproate, is more effective in treating difficult-to control epilepsy than other anti-epileptic regimens, according to a University of Washington report published online this week in Neurology, the journal of the American Academy of Neurology...
Electrical Activity In The Brain Likened To An OrchestraResearchers at the Norwegian University of Life Sciences (UMB) have developed a new method for detailed analyses of electrical activity in the brain. The method, recently published in Neuron, can help doctors and researcher to better interpret brain cell signals...
A More Ethical Way To Compare Epilepsy TreatmentsEpilepsy drug-switching study shows that using more ethical control groups could be the way forward for testing both drug efficacy and safety For the first time, a new research methodology recently approved by the Food and Drug Administration has been used to demonstrate that converting patients from one anti-epileptic drug to another - in this case, lamotrigine extended-rel...
Causative Gene May Differ Among Patients With Dravet SyndromeDravet syndrome is a severe genetic epilepsy that appears early in life. About 75 percent of cases can be attributed to mutations in the SCN1A gene encoding the sodium channel NaV1.1. The remaining patients with this syndrome are without a definitive molecular genetic diagnosis...