Traveling With Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) travelers have an increased risk of illness during trips to industrialized countries, but not to developing or tropical regions, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association...

Less Risk Of Inflammatory Bowel Disease In Warmer Climates
A long-term U.S. study published online in GUT has shown that living in sunnier climates may lower the chances of developing inflammatory bowel disease, especially in those aged 30 years or over. The researchers' findings, which support earlier European research, could potentially lead to new therapies and preventive measures...

IBD Emerges As A Global Disease
The incidence and prevalence of inflammatory bowel disease (IBD) are increasing with time and in different regions around the world, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association...

Endometriosis Raises Risk OF Inflammatory Bowel Disease
About one in ten women of child-bearing age suffers from endometriosis, a fairly common condition in which cells from the lining of the uterus grow in other areas of the body. According to a study published in Gut, women with endometriosis are almost twice as likely to develop inflammatory bowel disease compared to other females...

Why Does African Naked Mole-Rat Not Feel Pain With Acid
A new study has found out why the African naked mole-rat (Heterocephalus glaber) experiences no pain when exposed to acid. The African naked mole-rat is one of the most unusual mammals in the world. They live in large groups underground in dark narrow burrows where carbon dioxide (CO2) levels are extremely high...

Team Pinpoints Amino Acid Variation In Immune Response Gene Linked With Ulcerative Colitis
The association between the inflammatory bowel disease ulcerative colitis and a gene that makes certain cell surface proteins has been pinpointed to a variant amino acid in a crucial binding site that profoundly influences immune response to antigens, including gut bacteria, reports a team of researchers at the University of Pittsburgh, Cleveland Clinic, Carnegie Mellon Univers...

Personalized Treatment For Crohn's Disease A Step Closer Following Gene Mapping
Three new locations for Crohn's Disease genes have been uncovered by scientists at UCL using a novel gene mapping approach. The complex genetic and environmental causes of Crohn's Disease (CD) have long been difficult to untangle. CD, a type of Inflammatory Bowel Disease that affects about 100 to 150 people per 100,000 in Europe, is characterised by inflammation in the gastrointestinal tract...

Inflammatory Cues Modulate Goblet Cell Products Important For Intestinal Barrier Function
In a paper published in the December 2011 issue of Experimental Biology and Medicine, a team of scientists at the University of Illinois, Urbana-Champaign led by Rex Gaskins, PhD have demonstrated that both microbial and host inflammatory factors modulate sulfomucin production in a human cell line, LS174T, that models intestinal goblet cells...

Anti-Inflammatory Polyphenols Discovered In Apple Peels
Here's another reason why "an apple a day keeps the doctor away" - according to new research findings published in the Journal of Leukocyte Biology*, oral ingestion of apple polyphenols (antioxidants found in apple peels) can suppress T cell activation to prevent colitis in mice...

An IBS Patient's Interpretation Of Symptom Severity Is Affected By Psychological Factors
A patient's viewpoint of the severity of irritable bowel syndrome (IBS) symptoms can be influenced not only by physical symptoms of IBS but broader psychological problems, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association...

Inflammatory Bowel Disease Associated With Increased Skin Cancer Risk
Certain patients with inflammatory bowel disease (IBD) may have an increased risk of skin cancer, which is intensified by the use of immunosuppressant medications , according to two new studies in Gastroenterology, the official journal of the American Gastroenterological Association. Immunosuppressants are commonly used in the treatment of IBD...

Some Colon Tumors Caused By Common Bacteria Altering Peroxide-Producing Gene
Working with lab cultures and mice, Johns Hopkins scientists have found that a strain of the common gut pathogen Bacteroides fragilis causes colon inflammation and increases activity of a gene called spermine oxidase (SMO) in the intestine...

Stopping Autoimmunity In The NIK Of Time; CX3CR1: A Protein With Guts
IMMUNOLOGY: Stopping autoimmunity in the NIK of time Immune cells known as T cells play a key role in ridding the body of dangerous microbes. However, if they are not kept under control properly they can attack the body's own tissues and cells and cause autoimmunity...

Antibiotic-Associated Diarrhea Responds To Probiotics
'Good bugs' look promising as anti-inflammatory agent for patients with ulcerative colitis, psoriasis, chronic fatigue syndrome In four different studies presented at the American College of Gastroenterology's (ACG) 76th Annual Scientific meeting in Washington, DC, researchers explored the effectiveness of probiotics for antibiotic-associated diarrhea; as an anti-inflammat...

Effective Treatment For C. difficile, Inflammatory Bowel Disease - Fecal Microbiota Transplants
Growing evidence for the effectiveness of fecal microbiota transplants as a treatment for patients with recurrent bouts of Clostridium difficile (C.difficile) associated diarrhea is presented in three studies -- including a long-term follow-up of colonoscopic fecal microbiota transplant (FMT) for recurrent C...