Homing Molecules Eliminate Prions In The BrainToxic prions in the brain can be detected with self-illuminating polymers. The originators, at Link0ping University in Sweden, has now shown that the same molecules can also render the prions harmless, and potentially cure fatal nerve-destroying illnesses...
Mad Cow Disease In California The USA's fourth case of bovine spongiform encephalopathy (BSE), also known as Mad Cow Disease has been detected in a dairy cow in central California, USDA's Chief Veterinary Office, John Clifford announced yesterday. Clifford stresses that it is safe to eat beef and drink cow's milk and that existing high standards to protect the public's food supply is ongoing...
Ozone Treated Water V. Lethal Microbial MaterialA University of Alberta research team has discovered that technology commonly used to decontaminate food industry equipment can also rid meat processing plants of lethal microbial material responsible for the human version of the ailment Mad Cow disease...
Most Lethal Known Species Of Prion Protein IdentifiedScientists from the Florida campus of The Scripps Research Institute have identified a single prion protein that causes neuronal death similar to that seen in "mad cow" disease, but is at least 10 times more lethal than larger prion species...
First Mouse Model To Study Important Aspect Of Alzheimer'sHirano bodies are almost indescribably tiny objects found in nerve cells of people suffering from conditions such as Alzheimer's, mad cow and Lou Gehrig's diseases. Yet for decades, researchers weren't sure if these structures helped cause the conditions or appeared after onset of the disease and had some other role...
Cellular Stress Can Induce Yeast To Promote Prion FormationIt's a chicken and egg question. Where do the infectious protein particles called prions come from? Essentially clumps of misfolded proteins, prions cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, in humans and animals. Prions trigger the misfolding and aggregation of their properly folded protein counterparts, but they usually need some kind of "seed" to get started...
Tracking Down BSE And Creutzfeldt-Jakob DiseasePrion diseases such as Creutzfeldt-Jakob disease in humans and bovine spongiform encephalopathy (BSE) in cattle are transmissible neurodegenerative diseases linked to the aggregation of the prion protein in the central nervous system. It is known that the aggregation of prion proteins promotes neuronal decay with fatal consequences for the infected individual...
Rinderpest Is Dead; Second Disease In History Declared EradicatedThe Romans couldn't beat it when they ruled the world, but today in Rome the UN has declared the eradication of rinderpest, the second disease in all of human history to be successfully wiped out after smallpox. Scientists are celebrating victory over a deadly animal disease that cattle herders around the world have dreaded for millennia...
Drugs Being Developed To Tackle CJD Could Also Help Prevent Alzheimer'sScientists funded by the Medical Research Council (MRC) and Science Foundation Ireland (SFI) have identified two antibodies which could help block the onset of Alzheimer's disease in the brain. The antibodies, ICSM-18 and ICSM-35, were already known to play a crucial role in preventing 'protein misfolding', the main cause of Creutzfeldt-Jakob disease (CJD), the human form of mad cow disease...
Fast, Sensitive Blood Test For Human Prion DiseaseWHAT: Scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), report that they have developed a method -10,000 times more sensitive than other methods - to detect variant Creutzfeldt-Jacob disease (vCJD) in blood plasma. vCJD is a type of prion disease in humans that leads to brain damage and death...
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