Established Cancer Vaccine Works Better In Tandem With FDA-Approved Kidney Transplant DrugA team from the Perelman School of Medicine and the Abramson Family Cancer Research Institute at the University of Pennsylvania found that the FDA-approved drug daclizumab improved the survival of breast cancer patients taking a cancer vaccine by 30 percent, compared to those patients not taking daclizumab. This proof-of-concept study is published this week in Science Translational Medicine...
More Genes Discovered In The Fight Against Breast CancerIn a study published in Nature, researchers describe nine new genes that drive the development of breast cancer. This takes the tally of all genes associated with breast cancer development to 40. The team examined all the genes in the genomes of 100 cases of breast cancer...
Potential Breast Cancer Vaccine Combination TherapyA vaccine that targets cancer cells in combination with the drug letrozole, a standard hormonal therapy against breast cancer, significantly increased survival when tested in mice, a team of UC Davis investigators has found. The findings were published in the journal Clinical Cancer Research...
Marker To Identify, Attack Breast Cancer Stem CellsBreast cancer stem cells wear a cell surface protein that is part nametag and part bull's eye, identifying them as potent tumor-generating cells and flagging their vulnerability to a drug, researchers at The University of Texas MD Anderson Cancer Center report online in Journal of Clinical Investigation...
Apigenin Slowed Progression Of Breast Cancer Accelerated By Hormone Replacement TherapyApigenin, a natural substance found in grocery store produce aisles, shows promise as a non-toxic treatment for an aggressive form of human breast cancer, following a new study at the University of Missouri. MU researchers found apigenin shrank a type of breast cancer tumor that is stimulated by progestin, a synthetic hormone given to women to ease symptoms related to menopause...
Proper Radiotherapy Targeting While The Patient Is Breathing Radiotherapists are constantly battling in order to administer the correct dose of radiotherapy, as respiratory movement during radiotherapy poses a certain risk that a tumor receives either a dose that is insufficient, or the surrounding healthy tissue is being subjected to a potentially toxic over-dose. Dr...
Staggered Cancer Drug Delivery Better Than All In One Go The fact that treating cancer patients with multiple drugs often results in better outcomes than a single drug treatment is long been known amongst the medical profession. However, a MIT study published in the May 11 issue of Cell has just demonstrated that the order and timing of administering drugs may also have a dramatic impact...
Cancer In The Elderly: Research Fails To Keep Up With Demographic ChangeNew research showing that almost half of 13,000 patients with head and neck cancers had other health-related problems at the same time was one of the presentations in a special session at the 31st conference of the European Society for Radiotherapy and Oncology (ESTRO 31) [1]. The session highlighted the effect of the demographic time bomb caused by an increasingly ageing population...
Predicting Breast Cancer Response To ChemotherapyChemotherapy is a major first line defense against breast cancer. However a patient's response is often variable and unpredictable. A study published in BioMed Central's open access journal BMC Medical Genomics shows that 'gene expression signatures' for TOP2A and β-tubulin can be used to predict the outcome of chemotherapy...