Blood-Forming Stem Cells' Growth IdentifiedScientists with the new Children's Research Institute at UT Southwestern Medical Center have identified the environment in which blood-forming stem cells survive and thrive within the body, an important step toward increasing the safety and effectiveness of bone-marrow transplantation. Institute investigators led by Dr...
A 'Disruptive Science' Ready For Commercial Development - Gene TherapyThe time for commercial development of gene therapy has come. Patients with diseases treatable and curable with gene therapy deserve access to the technology, which has demonstrated both its effectiveness and feasibility, says James Wilson, MD, PhD, Editor-in-Chief of Human Gene Therapy in a provocative commentary and accompanying videocast...
Chemists Unlock Potential Target For Drug DevelopmentA receptor found on blood platelets whose importance as a potential pharmaceutical target has long been questioned may in fact be fruitful in drug testing, according to new research from Michigan State University chemists. A team led by Dana Spence of MSU's Department of Chemistry has revealed a way to isolate and test the receptor known as P2X1...
New Drug Labels For Kidney Disease PatientsThe U.S. Food and Drug Administration (FDA) recently recommended that clinicians be more conservative when they prescribe chronic kidney disease (CKD) patients with drugs that treat red blood cell deficiencies. But the drug label's recommendations fall short, according to two commentaries appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN)...
Blood Clots After Hip Or Knee Replacement - Study Looks At Prevalence According to a study in the January 18 issue of JAMA, approximately 1 in every 100 patients undergoing knee replacement surgery, and 1 in every 200 patients undergoing hip replacement surgery who use current preventive medications for venous thromboembolism (VTE; a blood clot that develops within a vein that might become serious), will develop VTE before being discharged from hospital...
Analysis Examines Rate Of In-Hospital Blood Clots Following Hip Or Knee ReplacementAccording to a study in the January 18 issue of JAMA reveals, approximately 1 in every 100 patients undergoing knee replacement surgery and 1 in every 200 patients undergoing hip replacement surgery who use current preventive medications for venous thromboembolism (VTE; a blood clot that develops within a vein that might become serious), will develop VTE before being discharged from hospital...
Annual Bleeding Events And Frequency Of Infusions Reduced By Preventive Hemophilia A TreatmentA Rush University Medical Center led international research team has announced that a treatment to prevent bleeding episodes in children with hemophilia A also is effective for adolescents and adults. The preventive therapy will "optimize care for hemophilia patients of all ages by stopping unexpected bleeding events that can have a detrimental impact on the lives of patients," said Dr...
Circulating Tumor Cells Analyzed In Patients With Lung CancerResearchers have developed a method to analyze circulating tumor cells in the blood of patients with non-small cell lung cancer. This method, which can analyze a sample size as small as three cells, may allow clinicians to track cancer progress and treatments and could help them develop new therapies...
Test All Hospitalized Patients For Blood Glucose Levels, Experts SayHyperglycemia, or high blood sugar (glucose) levels, is a common, serious and expensive health care problem in hospitalized patients that is linked to an increased risk of health complications and mortality. It can also affect non-diabetic hospitalized patients. According to observational studies, 32 to 38% of patients in community hospitals suffer from hyperglycemia...
Dialysis Treatments Go Green Solar power can help offset high utility costs and make hemodialysis treatments more environmentally friendly, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). The findings point the way to a 'green dialysis' future where utilities and other consumables are no longer taken for granted but are used and reused wisely...