Distinguishing Between The Forgetful And Those At Risk Of Alzheimer's Disease
It can be difficult to distinguish between people with normal age-associated memory loss and those with amnestic mild cognitive impairment (aMCI). However people with aMCI are at a greater risk of developing Alzheimer's disease (AD), and identification of these people would mean that they could begin treatment as early as possible...

Genes Linked To Alzheimer's Are The Same For Early- And Late-Onset
The same gene mutations linked to inherited, early-onset Alzheimer's disease have been found in people with the more common late-onset form of the illness. The discovery by researchers at Washington University School of Medicine in St. Louis may lead doctors and researchers to change the way Alzheimer's disease is classified...

Alzheimer's Disease May Spread By 'Jumping' From One Brain Region To Another
For decades, researchers have debated whether Alzheimer's disease starts independently in vulnerable brain regions at different times, or if it begins in one region and then spreads to neuroanatomically connected areas...

Protein Structures Offer Clues To Breast Cancer, Alzheimer's Treatment, Prevention
Using some of the most powerful nuclear magnetic resonance equipment available, researchers at the University of California, Davis, are making discoveries about the shape and structure of biological molecules - potentially leading to new ways to treat or prevent diseases such as breast cancer and Alzheimer's disease...

Alzheimer's-Related Protein In Brains Of Healthy Adults May Shed Light On Earliest Signs Of Disease
Researchers from the Center for Vital Longevity at the University of Texas at Dallas and UT Southwestern Medical Center have completed a large-scale neuroimaging study of healthy adults from age 30 to 90 that measured beta-amyloid protein - a substance whose toxic buildup in the brain is a diagnostic marker for Alzheimer's disease...

Alzheimer's Disease May Spread By 'Spreading' From One Brain Region To Another
The way in which Alzheimer's Disease spreads in the brain has been the subject of debate for many years. Two opposing theories have the disease starting independently in weakened brain regions over time, or it beginning in one region and then spreading neuroanatomically connected areas...

Brain Energy Metabolism Improved By Decaffeinated Coffee
Researchers from Mount Sinai School of Medicine have discovered that decaffeinated coffee may improve brain energy metabolism associated with type 2 diabetes. This brain dysfunction is a known risk factor for dementia and other neurodegenerative disorders like Alzheimer's disease. The research is published online in Nutritional Neuroscience...

Prion-Like Protein Plays A Key Role In Storing Long-Term Memories
Memories in our brains are maintained by connections between neurons called "synapses"...

12/15-Lipoxygenase Protein May Help Control Alzheimer's
Researchers at the Temple University's School of Medicine recently identified a protein in the brain that could have a major role in regulating the creation of amyloid beta, the major component of plaques implicated in the development of Alzheimer's disease...

Protein In The Brain Could Be A Key Target In Controlling Alzheimer's
A protein recently discovered in the brain could play a key role in regulating the creation of amyloid beta, the major component of plaques implicated in the development of Alzheimer's disease, according to researchers at Temple University's School of Medicine...

Infrared Analysis Of White Blood Cells Is A Promising Strategy For Diagnosis Of Alzheimer's Disease
Spanish researchers, led by Pedro Carmona from the Instituto de Estructura de la Materia in Madrid, have uncovered a new promising way to diagnose Alzheimer's disease more accurately. Their technique, which is non-invasive, fast and low-cost, measures how much infrared radiation is either emitted or absorbed by white blood cells...

Stimulating Cognitive Activity Lowers Risk Of Alzheimer's
Findings published Online First by Archives of Neurology, a JAMA/Archives journal, show that people who keep their brain active throughout their lives with cognitively stimulating activities like reading, writing and playing games seem to have lower levels of the β-amyloid protein, which is the major part of the amyloid plaque in Alzheimer disease...

Alzheimer's Neurons Induced From Pluripotent Stem Cells
Led by researchers at the University of California, San Diego School of Medicine, scientists have, for the first time, created stem cell-derived, in vitro models of sporadic and hereditary Alzheimer's disease (AD), using induced pluripotent stem cells from patients with the much-dreaded neurodegenerative disorder...

Cognitive Impairment Seems Common Among Older Men
The Mayo Clinic released its study of aging report today and announced that more than six percent of Americans, aged seventy to eighty-nine years, suffered from mild cognitive impairment (MCI). They also state that the data show more men are affected than women, and those with only high school education seem more affected than those with some level of higher education...

New Discoveries In Cell Aging
A group of researchers led by the Institute of Biotechnology and Biomedicine (IBB) and Universitat Autonoma de Barcelona (UAB) can now quantify with precision the effect of protein aggregation on cell aging processes using Escherichia coli bacteria and the molecule which triggers Alzheimer's disease as models. Scientists demonstrated that the effect can be predicted before it occurs...