Cosmetic Animation

New Epigenetic Player In Mental Retardation And Facial Birth Defects
A subtle mutation affecting the epigenome - a set of dynamic factors that influence gene activity - may lead to an inherited form of mental retardation that affects boys, find researchers at Children's Hospital Boston. The disorder, which also involves cleft lip or cleft palate, appears to hinge on an enzyme working in a biological pathway that may offer several potential drug targets...

Research Sheds Light On Early Embryogenesis, Genetic Disease
Chromosome 22q11 deletion syndrome (also known as DiGeorge syndrome) is the most common human chromosome deletion syndrome, having an estimated incidence of at least one in 4,000 live births...

Novel Genes Associated With Risk For Oral Cleft Malformation Identified
An international consortium of scientists, led by researchers at Johns Hopkins University has identified two genes that when altered are closely associated with cleft lip and/or cleft palate. Cleft lip and cleft palate are among the world's most common congenital malformations and occur in one in every 700 births...

News From The Journal Of Clinical Investigation, April 26, 2010
NEUROBIOLOGY: Too hot to handle: how heat causes pain Our body detects heat above 43 degrees Celsius as painful. The main detector of noxious heat is the protein TRPV1 on pain-sensing sensory nerve cells. Exactly how TRPV1 sensitivity to heat is regulated has not been clearly determined...

People With Facial Paralysis More Socially Adjusted Than Previously Thought
A smile means happiness, a frown sadness, a raised brow surprise. Even when languages and cultures differ, people have this universal form of communication. But Moebius syndrome, a rare congenital condition causing facial paralysis, can rob people of this basic connection, affecting social interaction...

Breakthrough For Babies Born With Severe Cleft Palates After Experiments At ISIS
Scientists working on a treatment for babies born with cleft palates have made a promising breakthrough and the first clinical trials are planned for early next year...

Team Approach Provides Better Care For Children With Cleft Lip And Palate
Children with a cleft lip or cleft palate are more likely to receive recommended age-appropriate health care when that care is provided by an interdisciplinary team rather than an individual provider. In a study encompassing three states, Arkansas, Iowa and New York, 24% of participants were not receiving team care...

Growth Factor Gene Shown To Be A Key To Cleft Palate
Cleft palate has been linked to dozens of genes. During their investigation of one of these genes, researchers at Washington University School of Medicine in St. Louis were surprised to find that cleft palate occurs both when the gene is more active and when it is less active than normal...

Growth Factor Gene Shown To Be A Key To Cleft Palate
Cleft palate has been linked to dozens of genes. During their investigation of one of these genes, researchers at Washington University School of Medicine in St. Louis were surprised to find that cleft palate occurs both when the gene is more active and when it is less active than normal...

Pitt Researcher To Co-Direct National Consortium On Facial Birth Defects
Researchers at the University of Pittsburgh and the University of Iowa will lead a $9 million, five-year initiative to study the cause of facial birth defects. The FaceBase Consortium will create an encyclopedic database of how the faces of children develop and what goes wrong to cause malformations...

Progress Report On Cleft Palate Surgery In Developing Countries
Craniofacial surgeons around the world are striving toward a critical goal: making high-quality cleft palate and craniofacial reconstructive surgical services available to children in developing countries...

FaceBase Consortium Launched By NIDCR
Although about half of all birth defects involve the face and skull, scientists remain unclear about why most occur. To help families at risk for these conditions, what's needed is a comprehensive and systematic understanding of how the faces of healthy children develop and what goes awry to cause common malformations...

Titan Announces Award Of NIH Grant For Probuphine(R) Clinical Development
Titan Pharmaceuticals, Inc (Pink Sheets:TTNP) announced that the National Institutes of Health (NIH) has awarded a Research and Research Infrastructure Grand Opportunities grant to the company through the American Reinvestment and Recovery Act of 2009 (ARRA). The two year grant for Probuphine clinical development is expected to provide approximately $7...

PCE Exposure Increases Risk Of Birth Defects
Exposure to tetrachloroethylene (also known as perchlorethylene, PCE) may cause congenital birth defects. A study of expectant women exposed to PCE in drinking water, published in BioMed Central's open access journal Environmental Health, found an increased risk of oral clefts and neural tube defects in their children...

PSivida Corp Reports Favorable 12-Month Interim Safety And Efficacy Results From Iluvien™ Human PK Study
pSivida Corp, a leading drug delivery company, reported the interim 12-month safety and efficacy results from the first human pharmacokinetic study (PK Study) of Iluvien™. The study is being conducted by the Company's licensing partner Alimera Sciences. Iluvien is an intravitreal insert being developed for the treatment of diabetic macular edema (DME)...