Shedding Light On How Psychiatric Risk Gene Disrupts Brain DevelopmentScientists are making progress towards a better understanding of the neuropathology associated with debilitating psychiatric illnesses like bipolar disorder and schizophrenia. New research, published by Cell Press in the July 15 issue of the journal Neuron, reveals mechanisms that connect a known psychiatric risk gene to disruptions in brain cell proliferation and migration during development...
Single MRI Scan 'Could Help Diagnose Bipolar Disorder'A single MRI (magnetic resonance imaging) scan may soon help hundreds of thousands of people with bipolar disorder to get a faster, more accurate - and possibly life-saving - diagnosis, a leading researcher reported at the Royal College of Psychiatrists' International Congress...
California Full-Service Partnership Program Is Cost EffectiveFull-Service Partnerships (FSPs) are designed to do 'whatever it takes' to improve residential stability and mental health outcomes for homeless persons with serious mental illness. They are the cornerstone of California's Mental Health Services Act (MHSA) - one of the largest mental health policy experiments in recent history...
Lithium Therapy Improvement By Reduction Of Its ToxicityLithium is the most effective treatment for bipolar disorder. However, its use is limited because of neurological side effects and a risk for overdose-induced toxicity. Many of the beneficial effects of lithium are mediated by its inhibition of GSK-3 proteins, but whether this is the mechanism underlying its negative effects has not been determined...
What Is Schizoaffective Disorder? What Causes Schizoaffective Disorder?Schizoaffective disorder is characterized by a combination of schizophrenia and affective (mood) disorder symptoms - there is disagreement on whether it is a type of mood disorder or schizophrenia. However, most health care professionals (clinicians) agree it is mainly a form of schizophrenia; not all experts agree on whether it should be treated as a distinct disorder...
Revealing Lithium's Mode Of ActionThough it has been prescribed for over 50 years to treat bipolar disorder, there are still many questions regarding exactly how lithium works. However, in a study appearing in this month's Journal of Lipid Research, researchers have provided solid evidence that lithium reduces brain inflammation by adjusting the metabolism of the health-protective omega-3-fatty acid called DHA...
Double Success For Leading Cardiff NeuroscientistsTwo Cardiff University academics, both leaders in different aspects of neuroscience research, have received one of the leading honours in medical science. Professor Alun Davies, of the University's School of Biosciences, and Professor Nick Craddock, of the School of Medicine, have been elected Fellows of the Academy of Medical Sciences...