Greatly Increased Risk Of Reflux Disease Of Esophagus In Extremely Obese Children
Extremely obese children have a 40 percent higher risk of gastroesophageal reflux disease (GERD) and children who are moderately obese have a 30 percent higher risk of GERD compared to normal weight children, according to a Kaiser Permanente study published online in the International Journal of Pediatric Obesity...

Obese Children At Higher Risk Of GERD
A large US study found that compared to normal weight children, obese children have a higher risk of developing gastroesophageal reflux disease (GERD), a condition where stomach fluid flows up into the food pipe or esophagus, damaging the lining and possibly also raising the incidence of inflammation, asthma and coughs...

Origin Of Acid Reflux Disease Revealed By Molecular Imaging
Molecular imaging has uncovered what may be to blame for acid reflux disease, a painful and potentially dangerous illness that affects a sizeable percentage of the population...

FDA Accepts New Drug Application (NDA) For Rabeprazole Sodium Extended-Release 50 Mg For Patients With Gastroesophageal Reflux Disease (GERD)
Eisai Inc. (Headquarters: Woodcliff Lake, NJ; Chairman and CEO: Hajime Shimizu), a U.S. subsidiary of Eisai Co., Ltd. (Headquarters: Tokyo; President and CEO: Haruo Naito) announced that the U.S...

Axanum And Expanded Nexium Indication Rejected By FDA
The Food and Drug Administration (FDA), USA has denied approval of AstraZeneca's Axanum (aspirin plus esomeprazole magnesium) and an expanded indication for AstraZeneca's Nexium (esomeprazole magnesium). AstraZeneca received a CRL (Complete Response Letter) for the new drug application for Axanum tablets, as well as a CRL for the supplemental new drug application (sNDA) for Nexium...

FDA: Possible Fracture Risk With High Dose, Long-term Use Of Proton Pump Inhibitors
The U.S. Food and Drug Administration warned consumers and health care professionals about a possible increased risk of fractures of the hip, wrist, and spine with high doses or long-term use of a class of medications called proton pump inhibitors. The product labeling will be changed to describe this possible increased risk...

Hearburn, Acid Reflux Drugs May Raise Risk Of Bone Fracture Warns FDA
The US Food and Drug Administration (FDA) has warned that high dose, long term use of a class of drugs known as Proton Pump Inhibitors (PPIs), for conditions such as heartburn, acid reflux and gastric ulcers, carries an increased risk of bone fractures in the wrist, hip and spine...

Disagreement On Symptom-Reflux Association Analysis Parameters In Infants
Gastroesophageal reflux (GER), defined as passage of gastric contents into the esophagus is a normal process that occurs in healthy infants, children and adults. When GER causes troublesome symptoms and/or complications it is referred to as gastroesophageal reflux disease (GERD)...

Zegerid OTC Provides Greater And Faster Acid Control Than Prevacid 24HR According To Head-To-Head Clinical Study
Merck Consumer Care has announced results of a head-to-head clinical study showing that ZEGERID OTC™ offers greater and faster acid control than Prevacid® 24HR. While acid control is an industry standard measure for acid-reducing drugs, greater and faster acid control does not imply greater and faster heartburn symptom relief...

Weight Loss And Physical Activity Improve Symptoms Of GERD
Gastroesophageal reflux disease (GERD) is a debilitating problem for sufferers -- heartburn, difficulty swallowing, chest pain and acid reflux...

Mast Cell Tryptase Test May Aid In Diagnosis Of Eosinophilic Esophagitis
A pathology test may help doctors distinguish between two separate but overlapping esophageal disorders that require different courses of treatment, according to a study by researchers at the University of North Carolina at Chapel Hill...

Proton Pump Inhibitor DEXILANTTM (dexlansoprazole) Now Available In U.S. Pharmacies
Takeda Pharmaceuticals North America, Inc. today announced that DEXILANT™ (dexlansoprazole) delayed release capsules are now available in United States (U.S.) pharmacies. Takeda recently announced that the product trade name for dexlansoprazole in the U.S. would be changed from KAPIDEX™ to DEXILANT...

Outcomes Of Patients Dismissed From The Hospital With Noncardiac Chest Pain
The growing number of Americans with cardiovascular disease has caused a heightened sensitivity in the evaluation of chest pain...

Women And Digestion: New Survey By Enzymedica Identifies Surprising Impact On Self Image And Well-Being
Digestive disorders are epidemic in the US and millions suffer regularly. While gas and bloating is common to both sexes, it is widespread in females, particularly during menses. Hoping to take a closer look at the problem, the digestive enzyme experts at The Enzyme Research Group, (ERG) in association with Enzymedica, Inc., conducted a survey of U.S. females...

Detection Of Precancerous Condition Improved By New Form Of Endoscopic Scanning
Cancer of the lower esophagus develops almost exclusively in patients with Barrett's esophagus, an otherwise benign complication of esophageal reflux that affects approximately 3 million Americans. Although the prognosis of patients diagnosed with esophageal cancer is poor, the chances of successful treatment increase significantly if the disease is detected at an early dysplastic stage...